Peroxisome proliferator-activated receptor (PPAR) gamma in cardiovascular disorders and cardiovascular surgery
نویسندگان
چکیده
منابع مشابه
Peroxisome proliferator-activated receptor gamma (PPAR-Î3) and its effects on the Cardiovascular system
Cardiovascular disease is one of the leading causes of death in the United States. Studying the pathogenesis of cardiovascular disease is, therefore, essential for the possible alleviation of such cases. Further knowledge could lead to more effective drug treatment. Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a nuclear receptor found in vascular-associated cells such as endothe...
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background: the peroxisome proliferator-activated receptor-γ (ppar-γ) is a nuclear hormone receptor. it is predominantly expressed in adipose tissue and as a receptor for thiazolidinediones, it has drawn attentions towards itself as a key molecule to trigger pathways involving in some diseases such as cancers, type 2 diabetes, inflammations and osteoporosis. a proline changed to alanine in codo...
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Objective(s): Herbal medicines are promising cancer preventive candidates. It has been shown that Punica granatum L. could inhibit angiogenesis and tumor invasion. In this study, we investigated whether the anti-angiogenic effect of pomegranate peel extract (PPE) is partly attributable to Peroxisome proliferator-activated receptors (PPARs) activation in the Human Umbilical Vein Endothelial Cell...
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Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that heterodimerize with the retinoid X receptor and then modulate the function of many target genes. Three PPARs are known: alpha, beta/delta, and gamma. The better known are PPAR-alpha and PPAR-gamma, which may be activated by different synthetic agonists, although the endogenous ligands are unknown. PPAR-alpha is invol...
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Osteoarthritis (OA) is among the most prevalent chronic human health disorders and the most common form of arthritis. It is a leading cause of disability in developed countries. This disease is characterized by cartilage deterioration, synovitis, and remodeling of the subchondral bone. There is not yet a satisfactory treatment to stop or arrest this disease process. Although several candidates ...
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ژورنال
عنوان ژورنال: Journal of Cardiology
سال: 2015
ISSN: 0914-5087
DOI: 10.1016/j.jjcc.2015.05.004